Coronavirus: Youth orchestra’s digital Tchaikovsky triumph

first_imgThe coronavirus pandemic has silenced many orchestras around the world. But the 70 young musicians who make up the Ulster Youth Orchestra have found a way to make themselves heard. – Advertisement – Under the supervision of Daniele Rustioni, the Ulster Orchestra’s chief conductor, they remotely recorded an ambitious piece of musical magic.The players followed Mr Rustioni’s conducting online before each individual recording was carefully patched together to create a spectacular orchestral experience. – Advertisement –last_img read more

Read More
Researchers track paths in brain cells

first_imgRecent research by Associate Professor of molecular and computational biology Don Arnold and molecular biology doctoral candidate Sarmad Al-Bassam successfully videotaped the movement of proteins within a brain cell, allowing scientists to study the inner workings of the brain — live.The project initially made use of green fluorescent protein, which is responsible for causing certain jellyfish to glow, to record the workings of the brain. Scientists have been using GFPs to view protein movement in cells for many years.Other members of the team included USC postdoctoral fellow Min Xu, who helped develop algorithms for analyzing the data, and Thomas J. Wandless, a professor of chemical and systems biology at Stanford University. The project was funded by a grant from the National Institute of Health, and the findings of the project were published in Cell Reports in July.As a continuation of the study, Arnold is now working on imaging the structure that turns the proteins around when they enter each cell’s axon. He turned in a paper for publishing which is currently undergoing academic review.Arnold said the idea of GFP kick-started his research.“In 1995, GFP came along and all of a sudden you could look at things live,” Arnold said.At the time, however, GFP alone could not produce any useful data for scientists aside from allowing scientists to view protein movement.“We wanted to look at proteins moving around in the cells, and the problem is that these proteins move along pathways, and all these pathways are moving simultaneously in the same space,” Arnold said. “When you see a vesicle moving along, it is impossible to tell which part of the pathway it’s in.”Arnold and his team began working on this project in 2008 to resolve this problem. The project aimed to block the pathway and then release all the proteins at once, in effect synchronizing protein movement.“We came up with the idea of halting this pathway and seeing everything go through at once,” he said.Al-Bassam was responsible for developing the techniques for synchronizing movement within the brain.“We adapted a chemical-genetic strategy that was originally devised to control the secretion of small peptides such as insulin and the human growth hormone for synchronizing the proteins,” Al-Bassam said. “The challenge was finding the unique conditions for visualizing the movement of vesicles containing fluorescent membrane proteins within neurons, which are some of the most difficult cells to work with.”The footage led scientists to discover some interesting facts about the inner workings of the brain.“We found that rather than being targeted specifically to the dendrites, vesicles carrying proteins initially enter both compartments, but then are stopped and prevented from moving beyond the initial segment of the axon,” Arnold said.The footage of a brain lit up with GFP stirred up interest among students as well as scientists.Isabel Shen, a sophomore majoring in neuroscience, said the video encouraged her to persue her own research.“It’s easy to be told about protein movement in lecture; it’s hard to visualize the process,” Shen said. “Not only does this video demonstrate the technology available to USC faculty, it deals with a topic relevant to everyone in every stage of aging and brain development.”last_img read more

Read More
High Court approval of GVC terms signals closing time on Ladbrokes Coral Plc

first_img Share Share Related Articles Submit Martin Lycka – Regulatory high temperatures cancel industry’s ‘silly season’ August 11, 2020 GVC hires ‘comms pro’ Tessa Curtis to re-energise media profile  August 25, 2020 The High Court of England & Wales has sanctioned the outright takeover of Ladbrokes Coral Plc by GVC Holdings, clearing the deals ‘recommended offer’ for investors.GVC governance clears another final hurdle towards securing its industry-changing takeover of Ladbrokes Coral, which this March received both its investor and UK Competition & Markets (CMA) approval.Updating stakeholders, GVC details that its deal is still on-time with the principal events calendar outlined in the scheme document published on 9 February 2018.Today’s update sees the High Court agree to investor provisions set-out in GVC’s combined Ladbrokes Coral corporate prospectus published on 9 February 2018.Ladbrokes Coral investors are guaranteed a 32.7 pence in cash and 0.141 new GVC shares for each share, representing a secured deal value of + £3.2 billion.Furthermore, GVC’s deal allows for an adjusted entitlement of up to 42.8 pence, dependent on the final judgement of the UK government’s Triennial Review on FOBTs wagering, which would increase the deal’s final transaction to + £4 billion.Securing High Court approval, Ladbrokes Coral will now move to delist/suspend its London FTSE main markets stock exchanging listing on Wednesday 28 March.GVC governance has reserved 273,000,000 shares at €0.01, for its enlarged trading on London’s main market on Thursday 29 March, incorporating Ladbrokes Coral investors. StumbleUpon GVC absorbs retail shocks as business recalibrates for critical H2 trading August 13, 2020last_img read more

Read More
THIS WEEK: FUFA’s Magogo cited in World Cup tickets scam

first_imgAddressing a press conference, Sewanyana said Magogo is unfit to serve as FUFA president. According to Ssewanyana, a journalist turned politician, Magogo engaged in actions as a commercial agent and then transferred without FIFA’s prior written consent tickets designated for Uganda.FUFA refuted Sewanyana’s claim that FIFA granted free tickets for the World Cup to FUFA for distribution.Share on: WhatsApp THIS WEEK: FUFA’s Magogo cited in World Cup tickets scamFederation of Uganda Football Association (FUFA) President Moses Magogo is facing a new storm of controversy ahead of his bid for a second term as head of FUFA in elections slated for August.Magogo has been accused of re-selling 177 tickets designated to Uganda for the 2014 FIFA world Cup by Allan Sewanyana, MP for Makindye West and shadow minister for sports.last_img read more

Read More
Adopt-A-Pet Dog of the Week

first_imgFacebook0Tweet0Pin0 Submitted by Adopt-A-Pet of SheltonThis sweetheart is Nelson, a male Boxer mix.  He loves to work for treats and knows many commands. Nelson is a healthy young boy who loves to romp and play as well as accompany you on long walks or play time in the back yard. He would do OK with older kids but smaller kids would not be appropriate because of Nelson’s size and level of energy.Nelson has lived with other dogs and gets along well with dogs his size but does not have an appreciation for the small dogs. He would do well either by himself or living with a buddy dog with his same level of energy and size. We do not know how he would do with a cat in the family. A secure fenced yard is a must for this inquisitive boy.We have lots of great dogs and always need volunteers to help them.  Visit our website at www.adoptapet-wa.org or contact Adopt-A-Pet, on Jensen Road in Shelton, at www.adoptapet-wa.org or contact us at thedoghouse3091@hotmail.com or (360) 432-3091.last_img read more

Read More
Monmouth Park Charity Hosts Annual Fashion Show

first_imgOCEANPORT – The Monmouth Park Charity Fund will be hosting the annual Winner’s Circle Fashion Show Luncheon on Friday, Aug. 24, at Monmouth Park Racetrack.The event will feature fashions presented by Coldwater Creek and Brooks Brothers. Female models will be provided courtesy of Model Team Management LLC of Ocean Grove.Paul G. Gaffney II, president of Monmouth University, will be the guest speaker. The event also will include the presentation of the Volunteer of the Year Award along with a gift auction and 50/50 raffle.Proceeds from the event will benefit the Monmouth Park Charity Fund whose mission it is to raise and distribute funds to nonprofit agencies throughout Monmouth County. These agencies provide services for health care, those at risk in the community and those in need of special services. Since the organization’s inception in 1946, more than $8.7 million has been distributed to local nonprofit agencies providing these services to residents of Monmouth County.Event co-chairs are Eleanor Williams and Denise Martin.Tickets are $55 per person and may be purchased by calling Mary Ann Martin at 732-571-5325 or emailing monmouthparkcharity@verizon.net.last_img read more

Read More
Leafs too much for Braves, outlast visitors 6-2 Sunday

first_imgWhen a team outshoots the opposition by almost a 3-1 margin, eventually cracks will begin to show in the castle wall.Nelson scored three unanswered goals in the third period to dump the Spokane Braves 6-2 in Kootenay International Junior Hockey League action Sunday afternoon at the NDCC Arena.The win enables Nelson to retain its second-place spot in the Murdoch standings, three points ahead of Grand Forks and fourth-place Castlegar Rebels.last_img

Read More
Consistently Consistent

first_imgWhatever your business strategy, it should be pursued consistently.If you have the lowest price because that is the value you intend to create, that should be how you compete. You confuse your customers and your employees when you sometimes try to capture more value. You don’t expect to pay more sometimes, and other times, pay less.If your strategy is to have the very best product, releasing and selling an inferior one damages your strategy. By releasing something that isn’t up to the standard you set, you lose the loyalty and the willingness to pay for something that is supposed to be of a higher quality, one worthy of a higher price.If your strategy is the best total solution, you don’t have to have the best price or the best product. Instead, you have to consistently deliver greater value through a combination of things designed to deliver greater value than competitive offerings. To execute this strategy you need to consistently create new solutions that match your client’s needs. When you stop collaborating and caring enough to do this work, you have broken your strategy.There are companies in every vertical that compete using each of these three strategies. It’s their consistency, however, that defines them in their space. You have to be consistently consistent in the execution of your strategy when it comes to differentiation, and when it comes to pricing.If you choose to compete by providing the lowest price and eliminating other value you might create, execute that strategy consistently and roll up all the targets who need that value. If you choose to create the best product money can buy, then refine your work and improve it, leaving no doubt that your product is better than any alternative. If you compete on the best overall solution, consistently execute that strategy, which means that you price according to the value you create, not what your competitor’s charge. Essential Reading! Get my first book: The Only Sale Guide You’ll Ever Need “The USA Today bestseller by the star sales speaker and author of The Sales Blog that reveals how all salespeople can attain huge sales success through strategies backed by extensive research and experience.” Buy Nowlast_img read more

Read More
Serena Williams shooting for Slam history

first_imgSerena’s 2017 triumph Down Under gave her the outright Open-era record for singles majors ahead of Steffi Graf’s 22, leaving only Court’s tally of 24 titles — 13 of which were earned in the amateur era before 1968 — for her to chase.Defending champion Caroline Wozniacki admitted Serena, already hailed by many as the greatest of all time, was an unknown quantity in Melbourne after sitting out the end of the 2018 season following the US Open blow-up.“I haven’t seen her play a match, so I don’t really know,” Wozniacki responded when quizzed about the American’s form. The Danish third seed preferred to concentrate on her own prospects, dismissing concerns health problems were affecting her game.Painful lossADVERTISEMENT Is Luis Manzano planning to propose to Jessy Mendiola? While the 21-year-old has appeared level-headed since her breakthrough at Flushing Meadows, she said she was still getting used to the spotlight.“For me one of my biggest goals is to be more mature, like to mature as a person,” the fourth seed said.“I feel like in a way I am, but in other parts I’m very, like, three years old mentality, you know? I feel like just levelling that out is one of my biggest goals I had during the off-season.”Local hopes will rest on Ashleigh Barty after the 22-year-old Queenslander went on a seven-match winning streak before losing the final of the Sydney International to Czech Petra Kvitova on Saturday.Maria Sharapova has failed to impress since returning from a doping ban and, now ranked 30, is looking some way from the player who won five Grand Slams. Two-time major champion and former number one Garbine Muguruza was another who had an injury-blighted 2018 which saw her drop out of the top 10.Sports Related Videospowered by AdSparcRead Next She achieved a career milestone last year to claim her maiden Grand Slam at Melbourne Park, but also revealed she was suffering the debilitating auto-immune condition rheumatoid arthritis.But the 28-year-old insisted she was managing her illness and was relishing the prospect of defending her crown.“All I can say is that I feel good. I feel like I’m hitting the ball well,” she said.Wozniacki’s vanquished opponent in last year’s final, Simona Halep, arrives in Australia with the world number one ranking and her confidence overflowing after winning the French Open.The Romanian said she was untroubled by the back injury that curtailed her 2018 season and was mentally stronger as a result of last year’s loss in the decider.“I didn’t want to think that much about that match because it was really painful to lose it, but I learned some things from that match,” she said.“Now I know how to manage better if that happens again.”Mature OsakaSecond-ranked Angelique Kerber has already indicated her priority for 2019 will be the French Open, the only Slam to elude the 30-year-old German in her career.Osaka is the leading contender among the younger generation of players, warming up for Melbourne by making the semi-finals of the Brisbane International. LATEST STORIES Kelly Oubre, Deandre Ayton lead Suns past West-leading Nuggets TS Kammuri to enter PAR possibly a day after SEA Games opening SEA Games hosting troubles anger Duterte MOST READ NEW YORK, NY – SEPTEMBER 08: Serena Williams of the United States reacts during her Women’s Singles finals match against Naomi Osaka of Japan on Day Thirteen of the 2018 US Open at the USTA Billie Jean King National Tennis Center on September 8, 2018 in the Flushing neighborhood of the Queens borough of New York City. Elsa/Getty Images/AFPSerena Williams has adopted a low profile ahead of the Australian Open, but rival players admit the American’s shadow looms large in Melbourne as she eyes a record-equalling 24th Grand Slam crown.Williams won her 23rd title and seventh at Melbourne Park while eight weeks pregnant two years ago, and now attempts to match Margaret Court’s mark of 24 singles majors on the Australian’s home soil.ADVERTISEMENT Private companies step in to help SEA Games hosting PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss SEA Games: Biñan football stadium stands out in preparedness, completion The 37-year-old’s last outing on tour was her meltdown in losing the US Open final to Naomi Osaka in September and she enters the season-opening Slam as the 16th seed.Yet she has proved in the past that such numbers mean little to her and Osaka said most in the locker room believed the veteran remains the one to beat in Melbourne.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine ‍football chiefSPORTSWin or don’t eat: the Philippines’ poverty-driven, world-beating pool stars“I’m pretty sure (that’s the case),” said the Japanese star.“But there’s a group of players that I think everyone thinks is very difficult to play against, especially in Grand Slams,” Osaka added. SEA Games: Biñan football stadium stands out in preparedness, completion LOOK: Joyce Pring goes public with engagement to Juancho Triviño LOOK: Joyce Pring goes public with engagement to Juancho Triviño Don’t miss out on the latest news and information. View commentslast_img read more

Read More
Message for National Heroes Day 2017 Leader of the Opposition Dr. Peter Phillips

first_img‘A GREAT HERITAGE, A GREAT LEGACY’Once again it is time for us to recognize and celebrate the achievements of our national heroes.  Collectively,their exploits and accomplishments have paved the way for Jamaica to move from plantation slavery to nationhood. The bravery and courage of Nanny of the Maroons and Sam Sharpe propelled us along the path from slavery to freedom. Paul Bogle and George William Gordon led the fight for social justice and access to land.Marcus Garvey gave Jamaicans the self-confidence to rise above their circumstances, and compete successfully with the best in the race of life.Alexander Bustamante’s deep commitment to the workers and Norman Manley’s confidence in Jamaica’s capacity for self-government charted the course from colonialism to nationhood. The journey from plantation slavery to nationhood has made us a proud visionary and ambitious people, always striving for excellence, committed to equality and social justice and caring for each other. However, we need to bear in mind that with each passing year fewer and fewer Jamaicans have any living memory of any of our heroes. It is therefore of the utmost importance that we utilize the media, the classroom and our creative artists to inform and educate our children of the great heritage and the great legacy that we have inherited.Today, as we celebrate our National Heroes; let us also pause to recognize the tremendous contributions of the thousands of our ordinary Jamaican citizens who have given and continue to give service way beyond the call of duty to keep Jamaica going. Particularly at this time, we pay tribute to the members of our security forces, who put their lives on the line battling violent criminals, often without adequate support.  We also pay respect to our teachers, health care workers, and the other public sector workers who often give of their personal time and resources, to keep the nation’s social services functioning in very difficult circumstances.  Respect is also due to the thousands of Jamaicans who give voluntary service through their citizens’ associations, neighbourhood watches or youth clubs, on behalf of their fellow citizens.These are the present day heroes, who by their collective effort remind us that the vision, hopes and aspirations of the founding heroes of our nation are still to be fully realized.  There are still too many suffering from poverty, joblessness and a lack of housing or access to land.  Too many of our children are left behind in our educational system without adequate preparation for responsible citizenship and the world of work. The Jamaica that our heroes lived worked and died for is one in which no citizen would be a squatter in the land of their birth. In that Jamaica no child would be left behind by an educational system which fails the majority of students. It would be a Jamaica in which every worker would have a fair share of the wealth they create and equal enjoyment the rights that our heroes secured for them.This Jamaica, however, can only be built by a political leadership that places the highest premium on integrity; and which is committed to the highest standards of public service while recognizing the importance of a partnership with the people they serveWe can best honour our heroes by providing this leadership in our various areas of endeavor as we rededicate ourselves to the task of building a Jamaica that offers opportunity to all its people, and where we all share and care for each other.Have a happy Heroes Day and may God bless you all and Jamaica land we love.last_img read more

Read More